|
Symbol Name ID |
Tk2
thymidine kinase 2, mitochondrial MGI:1913266 |
| Darker colors indicate more annotations |
| Human Phenotypes | Facial diplegia |
Dysphagia |
Difficulty walking |
Bulbar palsy |
Abnormal basal ganglia morphology |
Cerebral atrophy |
Dysarthria |
Irritability |
Motor deterioration |
Intellectual disability, progressive |
Hyporeflexia |
Inability to walk |
Loss of ability to walk in early childhood |
Infantile encephalopathy |
Developmental regression |
Motor delay |
Delayed gross motor development |
Seizure |
Generalized-onset seizure |
| Disease(s) Associated with TK2 | |||||||||||||||||||
| autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 3 | |||||||||||||||||||
| mitochondrial DNA depletion syndrome 2 |
| Mouse Phenotypes | abnormal nervous system morphology |
abnormal brain morphology |
abnormal astrocyte morphology |
abnormal spinal cord interneuron morphology |
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| Availability | Mouse Genotype | ||||
| Tk2tm1Mihi/Tk2tm1Mihi | |||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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